Versed

Section 8 - MEDICATION GUIDELINES

SEDATIVE / HYPNOTICS / ANTIPSYCHOTIC

Midazolam (VERSED) / Sedative / Hypnotic

DESCRIPTION

• It is a skeletal muscle relaxant that reduces tremors, induces amnesia, and reduces the incidence and recurrence of seizures.
• Depresses sub-cortical levels in CNS.

INDICATIONS

• Sedation for post resuscitation combativeness, combative head injury, intubations, pacing and cardioversion.
• Seizures, status epilepticus.

CONTRAINDICATIONS

• Pregnancy (relative contraindication), hypersensitivity to benzodiazepines, coma, acute narrow angle glaucoma, shock, alcohol intoxication.

PRECAUTIONS

• Hypotension, COPD, CHF, chronic renal failure, chills, elderly, debilitated.

DOSAGE

• INTUBATION: Initial dose, 2-5 mg IVP then 2-4 mg every 30 seconds to 1 minute.
• SEDATION, PACING, CARDIOVERSION: Initial dose 2-5 mg IVP then 2 mg every 30 second to 1 minute IVP. Max dose= 15 mg in the intubated patient. Can be given IM.07-.mg/kg with onset in approximately 15 minutes
• An IM injection requires immediate IV access upon sedation.
• HYPOTENSION responds well to Trendelenburg.
• Pediatrics refer to Handtevy System.