Anti-Fibrinolytic: Difference between revisions
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(Created page with "==Section 8 - MEDICATION GUIDELINES== ===8.19 ANTI-FIBRINOLYTICS=== ====Tranexamic Acid (TXA)==== '''DESCRIPTION''' * Inhibits both plasminogen activation and plasmin activi...") |
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* 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes. | * 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes. | ||
[[Category:Medication Guidelines| | [[Category:Medication Guidelines|0819]] | ||
Revision as of 18:29, 7 September 2018
Section 8 - MEDICATION GUIDELINES
8.19 ANTI-FIBRINOLYTICS
Tranexamic Acid (TXA)
DESCRIPTION
- Inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation. With massive bleeding this may help stabilize clot formation and decrease extravascular bleeding.
INDICATIONS
CONTRAINDICATIONS
- Isolated head injury
- Known hypersensitivity
- Age less than 16 years old
- Known pregnancy
PRECAUTIONS
- Rapid injection can cause hypotension
DOSAGE
- 1000 mg of TXA mixed in 100 ml or 250 ml of normal saline infused via IO or IV over 10 minutes.