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==Section 8 - MEDICATION GUIDELINES==
===SEDATIVE / HYPNOTICS / ANTIPSYCHOTIC===


====Ziprasidone (GEODON) / Antipsychotic====
'''DESCRIPTION'''
* An atypical antipsychotic acting as a dopamine antagonist that also affects other neurotransmitters to reduce psychosis and acute agitation.
'''INDICATIONS'''
* Used for the control of acute agitation in schizophrenic and/or severely agitated patients.
'''CONTRAINDICATIONS'''
* Persons known to have prolonged QTc intervals
** Only in high doses of 40-60 mg has shown a slight increase in QTc
* Known recent acute myocardial infarction
* Uncompensated heart failure
* Patients known to take other medications that also prolong the QTc interval
* Hypersensitivity to the medication.
'''PRECAUTIONS'''
* No clinically significant drug-drug interactions have been identified with other concomitantly administered EMS medications such as benzodiazepines.
'''DOSAGE'''
* 10 - 20 IM for adults based on the BARS scale for agitation.
* Not approved for use in pediatric patients.
'''ONSET OF ACTION'''
* Less than 15 minutes
* Peak effect 20-30 minutes
* Half-Life 2-5 hours


'''Behavioral Activity Rating Scale'''
{| class="wikitable"
|-
| 7|| Violent, requires restraint.
|-
| 6|| Extremely/continually active; not requiring restraint.
|-
| 5|| Signs of overt (physical or verbal) activity; calms down with instruction.
|-
| 4|| Quiet and awake (normal activity level).
|-
| 3|| Drowsy, appears sedated.
|-
| 2|| Asleep, but responds normally to verbal or physical contact.
|-
| 1|| Difficult or unable to arouse.
|}


'''Medications known to prolong the QTc (This table is not all inclusive)'''
{| class="wikitable"
|-
| Adderall|| Droperidol|| Procainamide
|-
| Amiodarone|| Effexor|| Propulsid
|-
| Anzemet|| Elavil|| Prozac
|-
| Avelox|| Erythromycin|| Seroquel
|-
| Betapace|| Haldol|| Tamoxifen
|-
| Cardene|| Lozol|| Zanaflex
|-
| Cerebyx|| Mellaril|| Zithromax
|-
| Detrol LA|| Norpace|| Zoloft
|}

[[Category:Medication Guidelines|Geodon]]