Vasopressin

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Section 8 - MEDICATION GUIDELINES

HORMONES / VITAMINS

Vasopressin / pituitary hormone

DESCRIPTION

  • Pituitary hormone that can cause vasoconstriction (pressor effect) of the splanchnic and portal vessels (and to a lesser extent of peripheral, cerebral, pulmonary, and coronary vessels). Also increases the smooth muscular activity of the bladder, GI tract, and uterus.

INDICATIONS

  • May be used as an alternative pressor to EPINEPHRINE in the treatment of adult shock refractory VF. May be useful for hemodynamic support in vasodilatory shock.

CONTRAINDICATIONS

  • Not recommended for responsive patients with coronary artery disease

PRECAUTIONS

  • Potent peripheral vasoconstrictor. Increased peripheral vascular resistance may provoke cardiac ischemia and angina.

DOSAGE

  • 40 U IV or IO (once) in Ventricular Fibrillation / Pulseless Ventricular Tachycardia